DocumentCode :
1829943
Title :
On the Alignment Space and its applications
Author :
Shen, Shi-Yi ; Wang, Kui ; Hu, Gang ; Xia, Shu-Tao
Author_Institution :
Sch. of Math., Nankai Univ., Tianjin
fYear :
2006
fDate :
22-26 Oct. 2006
Firstpage :
165
Lastpage :
169
Abstract :
The classic error-correcting codes are designed to correct substitution errors, in which the original symbol is replaced by a different symbol. The so called generalized errors include not only substitutions of symbols but also deletions and/or insertions of symbols. In the areas of computer science, information theory , cryptography and bioinformatics, sequences with generalized errors are discussed respectively for different aims. We describe generalized errors by mutation model which comes from bioinformatics. To deal with the sequences with generalized errors, we also need some type of metric to measure the distance of sequences with various lengths. The alignment distance is defined as the distance between the two sequences with generalized errors. The algorithms to calculate the alignment distance were studied in bioinformatics recently, such as Smith-Waterman dynamic programming algorithm and SPA algorithm. Under the alignment distance, we give the definition of the alignment space. To strictly describe the structure of the sequences with generalized errors, modular structure theory is introduced. A new and more strict proof of triangle inequality for alignment distance is thus given. As applications of the alignment space, the definition and construction of generalized error-correcting codes are studied in this paper. Some optimal codes with small length are listed. The error-correcting capability of random codes with large length is also presented. We discuss fault-tolerance complex in cryptography as another application of the alignment space at the end of the paper
Keywords :
biology computing; cryptography; dynamic programming; error correction codes; fault tolerance; SPA algorithm; Smith-Waterman dynamic programming algorithm; alignment distance; bioinformatics; cryptography; error-correcting codes; fault-tolerance complex; generalized errors; modular structure theory; optimal codes; Application software; Bioinformatics; Computer errors; Computer science; Cryptography; Dynamic programming; Error correction codes; Genetic mutations; Information theory; Length measurement;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Information Theory Workshop, 2006. ITW '06 Chengdu. IEEE
Conference_Location :
Chengdu
Print_ISBN :
1-4244-0067-8
Electronic_ISBN :
1-4244-0068-6
Type :
conf
DOI :
10.1109/ITW2.2006.323780
Filename :
4119278
Link To Document :
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