Parsimonious Design Principles for Motor Unit Models

Author

Lan Ban ; Shapiro, N.P. ; Lee, R.H.

Author_Institution

Georgia Inst. of Technol., Atlanta

fYear

2007

fDate

22-26 Aug. 2007

Firstpage

2412

Lastpage

2415

Abstract

Motor units are known to display type-specific differences in passive and active electrical properties, and attempts to predict motor unit type based on the measurement of membrane properties have been rather successful. Quantitative models of motoneurons have also grown in complexity and their predictive power is predicated upon the accurate description of basic membrane properties. This paper presents results from a modeling study which sought to specify a small and simple set of ";design rules"; that motoneurons might obey during type-specific differentiation.

Keywords

bioelectric phenomena; biomembranes; cellular biophysics; neurophysiology; physiological models; design rules; electrical properties; membrane properties; motoneurons; motor unit models; parsimonious design; type-specific differentiation; Analytical models; Biomedical engineering; Biomembranes; Computational modeling; Displays; Electric variables measurement; Immune system; Predictive models; Recruitment; Surface resistance; Algorithms; Cations; Cell Differentiation; Cell Membrane; Dendrites; Equipment Design; Humans; Models, Neurological; Models, Statistical; Models, Theoretical; Motor Neurons; Movement; Potassium Channels; Sodium Channels; Time Factors;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE

Conference_Location

Lyon

ISSN

1557-170X

Print_ISBN

978-1-4244-0787-3

Type

conf

DOI

10.1109/IEMBS.2007.4352814

Filename

4352814