A simulation-based study of reconstruction in Time-resolved Fluorescence Diffuse Optical Tomography in Cylindrical geometry

Author

Ducros, N. ; Da Silva, A. ; Dinten, J.-M. ; Peyrin, F.

Author_Institution

CEA-LETI MINATEC, Grenoble

fYear

2007

fDate

22-26 Aug. 2007

Firstpage

2639

Lastpage

2642

Abstract

The present paper is devoted to fluorescence diffuse optical tomography by using time resolved signals for the reconstruction of the 3D biodistribution of fluorescent probes embedded in biological tissues. The focus is made on the reconstruction of a methodology for an efficient exploitation of the time resolved data. The study is restricted to the examination of the three first moments of signals acquired in cylindrical geometry. The interest of temporal information upon cw information has been shown especially when only a limited number of views is available.

Keywords

biomedical optical imaging; fluorescence; image reconstruction; medical image processing; optical tomography; biological tissues; cylindrical geometry; fluorescence diffuse optical tomography; fluorescent probes; time resolved data reconstruction; Biological system modeling; Biological tissues; Biomedical optical imaging; Fluorescence; Geometrical optics; Geometry; Probes; Signal resolution; Solid modeling; Tomography; Computer Simulation; Phantoms, Imaging; Spectrometry, Fluorescence; Tomography, Optical;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE

Conference_Location

Lyon

ISSN

1557-170X

Print_ISBN

978-1-4244-0787-3

Type

conf

DOI

10.1109/IEMBS.2007.4352871

Filename

4352871