Sensitive detection of biomolecular chirality by nonlinear optical activity

Author

Verbiest, Thierry ; Kauranen, Martti ; Persoons, André

Author_Institution

Lab. of Chem. & Biol. Dynamics, Univ. of Leuven, Heverlee, Belgium

fYear

1994

fDate

25-29 Jul 1994

Firstpage

80

Lastpage

82

Abstract

We have studied nonlinear optical activity in second-harmonic generation from Langmuir-Blodgett monolayers of a synthetic chiral polymers. All observed effects are explained by a model that includes the contributions of both electric and magnetic dipole transitions to the second-order nonlinearity of the chiral surface. In this paper, we use samples of bacteriorhodopsin as an example to show that such nonlinear optical activity can be used as a sensitive probe of chiral environment of biological material

Keywords

Langmuir-Blodgett films; biophysics; biosensors; chirality; light polarisation; monolayers; optical films; optical harmonic generation; optical rotation; proteins; sensitivity; Langmuir-Blodgett monolayers; bacteriorhodopsin; biological material; biomolecular chirality; biosensors; chiral environment; chiral surface; electric dipole transitions; magnetic dipole transitions; nonlinear optical activity; second-harmonic generation; second-order nonlinearity; sensitive detection; synthetic chiral polymers; Atom optics; Biomedical optical imaging; Laser beams; Magnetic moments; Magnetization; Nonlinear optics; Optical polymers; Optical sensors; Optical surface waves; Polarization;

fLanguage

English

Publisher

ieee

Conference_Titel

Nonlinear Optics: Materials, Fundamentals, and Applications, 1994. NLO '94 IEEE

Conference_Location

Waikoloa, HI

Print_ISBN

0-7803-1473-5

Type

conf

DOI

10.1109/NLO.1994.470887

Filename

470887