Title :
Evaluation of a CCD-based tissue imaging system
Author :
MacDonald, J.H. ; Wells, K. ; Ott, R.J.
Author_Institution :
Inst. of Cancer Res., R. Marsden Hospital, Sutton, UK
Abstract :
A digital tissue imaging system based on a cooled charge coupled device (CCD) has been developed at the Physics Department of the Institute of Cancer Research. The system images low energy X-ray emissions and β particle emissions from a variety of isotopes, with a position resolution approaching 20 μm and sensitivity approaching 100%. Because of the frame-by-frame composite way in which images are constructed, the dynamic range of the system is 16 bit, limited only by the microcomputer used to acquire and store the images. Images have been obtained of isotope distributions in tissue with radioactivity levels which were too low to be detected using conventional technology. Room temperature operation of the CCD in the inverted mode has been investigated
Keywords :
CCD image sensors; X-ray imaging; beta-ray detection; computerised tomography; diagnostic radiography; emission tomography; radiation therapy; radioisotope imaging; β particle emissions; CCD-based tissue imaging system; cooled charge coupled device; digital tissue imaging system; inverted mode; isotope distributions; low energy X-ray emissions; position resolution; room temperature operation; Cancer; Charge coupled devices; Charge-coupled image sensors; Dynamic range; Energy resolution; Image resolution; Isotopes; Optical imaging; Physics; X-ray imaging;
Conference_Titel :
Nuclear Science Symposium, 1996. Conference Record., 1996 IEEE
Conference_Location :
Anaheim, CA
Print_ISBN :
0-7803-3534-1
DOI :
10.1109/NSSMIC.1996.591723
