Microfluidic Module System with Piezo Driven Microvalve for Synthesis of Radiopharmaceutical Products

This article presents a novel microfluidic module system for the synthesis of radiopharmaceutical products. As a main function a piezo-actuated diaphragm valve is produced with rapid prototyping procedures. A system for the automatic characterization of microvalves is described. The built microvalve is characterized by a very high throughput and low leakage rate even for gaseous media. The valve as other passive modules like mixer elements can be easily combined to a microfluidic system. The system makes the application of radiopharmaceutical products more effective and less costly intensive.