A computer simulation of the dynamic interaction between regional coronary flow and LV mechanics

Author

Naim, Karen L. ; Santamore, William P. ; Jaron, Dov

Author_Institution

Biomed. Eng. & Sci. Inst., Drexel Univ., Philadelphia, PA, USA

fYear

1994

fDate

3-6 Nov 1994

Firstpage

97

Abstract

A model was developed to study the time-varying relation between regional LV mechanics, local coronary flow and some of the important underlying metabolic factors. The authors´ previous LV model was extended to simulate the changes in regional behavior of the heart imposed by modifications in local coronary flow. This was accomplished by quantifying the relation between regional heart metabolism and function. The resulting model is capable of predicting the acute changes in heart function during the development of myocardial ischemia following coronary stenosis

Keywords

biology computing; biomechanics; cardiology; digital simulation; haemodynamics; physiological models; acute changes; computer simulation; coronary stenosis; dynamic interaction; heart regional behavior; left ventricular mechanics; myocardial ischemia; regional coronary flow; underlying metabolic factors; Biochemistry; Biomedical engineering; Computational modeling; Computer simulation; Erbium; Heart; Ischemic pain; Myocardium; Predictive models; Supply and demand; Surgery;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE

Conference_Location

Baltimore, MD

Print_ISBN

0-7803-2050-6

Type

conf

DOI

10.1109/IEMBS.1994.412086

Filename

412086