Title :
A computer simulation of the dynamic interaction between regional coronary flow and LV mechanics
Author :
Naim, Karen L. ; Santamore, William P. ; Jaron, Dov
Author_Institution :
Biomed. Eng. & Sci. Inst., Drexel Univ., Philadelphia, PA, USA
Abstract :
A model was developed to study the time-varying relation between regional LV mechanics, local coronary flow and some of the important underlying metabolic factors. The authors´ previous LV model was extended to simulate the changes in regional behavior of the heart imposed by modifications in local coronary flow. This was accomplished by quantifying the relation between regional heart metabolism and function. The resulting model is capable of predicting the acute changes in heart function during the development of myocardial ischemia following coronary stenosis
Keywords :
biology computing; biomechanics; cardiology; digital simulation; haemodynamics; physiological models; acute changes; computer simulation; coronary stenosis; dynamic interaction; heart regional behavior; left ventricular mechanics; myocardial ischemia; regional coronary flow; underlying metabolic factors; Biochemistry; Biomedical engineering; Computational modeling; Computer simulation; Erbium; Heart; Ischemic pain; Myocardium; Predictive models; Supply and demand; Surgery;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.412086
