• DocumentCode
    1856148
  • Title

    A high efficiency micromachined artificial lung

  • Author

    Potkay, Joseph A.

  • Author_Institution
    Dept. of Veterans Affairs Med. Center, Adv. Platform Technol. Center (APT Center), Cleveland, OH, USA
  • fYear
    2009
  • fDate
    21-25 June 2009
  • Firstpage
    2234
  • Lastpage
    2237
  • Abstract
    This paper presents the design, fabrication and first results for a microfabricated artificial lung with feature sizes that are comparable to that of the natural lung. The device is targeted at an increased gas transfer efficiency and portability compared to its current commercial alternatives and boasts the thinnest silicone gas transfer membrane and the lowest membrane diffusional resistance for a silicone-based device to date. Devices with 15 mum-thick membranes and 30 mum-tall channels achieved membrane and blood-side diffusional resistances of 27 times 103 and 118 times 103 ml-1middotsmiddotcm2middotcmHg, respectively, for oxygen.
  • Keywords
    artificial organs; bioMEMS; biodiffusion; biomembranes; microfabrication; silicones; SiO2; artificial lung microfabrication; membrane diffusional resistance; micromachined device fabrication; silicone gas transfer membrane; silicone-based device design; size 15 mum; size 30 mum; Biomembranes; Blood; Carbon dioxide; Diseases; Exchange rates; Fabrication; Humans; Immune system; Lungs; Surface resistance; Artificial lung; Micro-molding; Microfabrication; PDMS; Silicone; blood oxygenator; diffusion membrane;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International
  • Conference_Location
    Denver, CO
  • Print_ISBN
    978-1-4244-4190-7
  • Electronic_ISBN
    978-1-4244-4193-8
  • Type

    conf

  • DOI
    10.1109/SENSOR.2009.5285592
  • Filename
    5285592