Title :
High efficiency flow electrochemical immuno sensors using 3-D comb electrodes made of magnetic alloy
Author :
Honda, Nobuo ; Katagiri, Takashi ; Inaba, Masashi ; Yamaguchi, Yutaka ; Shoji, Shuichi ; Sato, Hirotaka ; Homma, Takayuki ; Osaka, Tetsuya
Author_Institution :
Dept. of Electron., Waseda Univ., Tokyo, Japan
Abstract :
An electrochemical immunoassay using micro-fabricated three dimensional (3-D) comb electrodes made of magnetic alloy was tested. The dimensions of the electrodes are 10 μm in width and 20 μm in height, with 20 μm spacing in between, and the 30 pairs of anode and cathode electrodes made up a single sensor. The sensitivity of alpha-fetoprotein (AFP) immunoassay using magnetic beads has been found to increase due to an increasing of apparent enzyme activity near the electrodes.
Keywords :
biosensors; electrochemical sensors; electrodes; enzymes; 3D comb electrodes; alpha-fetoprotein immunoassay; anode electrodes; cathode electrodes; electrochemical immuno sensors; enzyme activity; magnetic alloy; magnetic beads; single sensor; Anodes; Biochemistry; Cathodes; Copper; Electrodes; Electronic equipment testing; Magnetic analysis; Magnetic sensors; Resists; Substrates;
Conference_Titel :
Nanotechnology, 2005. 5th IEEE Conference on
Print_ISBN :
0-7803-9199-3
DOI :
10.1109/NANO.2005.1500767
