• DocumentCode
    1858014
  • Title

    Numerical model for DNA size separation using nanostructured matrix

  • Author

    Itoh, Shintaro ; Tagaya, Y. ; Isahaya, N. ; Fukuzawa, Kenji ; Hedong Zhang

  • Author_Institution
    Dept. of Micro-Nano Syst. Eng., Nagoya Univ., Nagoya, Japan
  • fYear
    2012
  • fDate
    4-7 Nov. 2012
  • Firstpage
    32
  • Lastpage
    34
  • Abstract
    Numerical model for DNA separation using nanostructure was proposed. By the model calculation, we can predict the migration time of the molecule that passes through the molecular sieve. In the numerical model, we assumed the DNA molecule to be a sphere with radius Rg, which is a gyration radius, and modeled its Brownian motion by a random walk. Calculation results showed good agreement with those of experiments and we confirmed the validity of the proposed model.
  • Keywords
    Brownian motion; DNA; biological techniques; molecular biophysics; molecular configurations; molecular sieves; nanobiotechnology; nanoporous materials; numerical analysis; porosity; separation; Brownian motion; DNA size separation; gyration radius; molecular sieve; molecule migration time; nanostructured matrix; numerical model; random walk;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro-NanoMechatronics and Human Science (MHS), 2012 International Symposium on
  • Conference_Location
    Nagoya
  • Print_ISBN
    978-1-4673-4811-9
  • Type

    conf

  • DOI
    10.1109/MHS.2012.6492396
  • Filename
    6492396
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1858014