Title :
Biomechanical properties of red blood cell through the motion inside a micro-channel
Author :
Tsai, Chia-Hung Dylan ; Kaneko, Makoto ; Sakuma, Shinya ; Arai, Fumihito
Author_Institution :
Dept. of Mech. Eng., Osaka Univ., Suita, Japan
Abstract :
The behavior of red blood cell passing through a micro-channel can be divided into two phases, where one is the transition phase and the other is the steady-state phase. This paper focuses on the in-depth understanding of the transition phase from the viewpoint of the physical significance. By using the customized threshold for classifying two phases on the red blood cells from different subjects, we show that the deformation of the cells plays a critical role in the location of the transition point. The technique of locating the transition point is improved by analyzing the evolution of R2 value, which is used for locating the linear portion of motion profile. The experimental results are presented for supporting the proposed methods.
Keywords :
biomechanics; blood; cellular transport; deformation; microchannel flow; biomechanical properties; cell deformation; customized threshold; micro-channel; motion profile; red blood cell; steady-state phase; transition phase; transition point location;
Conference_Titel :
Micro-NanoMechatronics and Human Science (MHS), 2012 International Symposium on
Conference_Location :
Nagoya
Print_ISBN :
978-1-4673-4811-9
DOI :
10.1109/MHS.2012.6492475