Title :
2-dimensional potassium ion image sensor aiming for Label-free dynamic imaging of living-cell activity
Author :
Atsumi, K. ; Masaki, Y. ; Noda, T. ; Hattori, T. ; Takao, H. ; Ishida, M. ; Sawada, K.
Author_Institution :
Toyohashi Univ. of Technol., Toyohashi, Japan
Abstract :
This research succeeded in capturing the behavior of potassium ion as moving image for the first time. A 2-dimensional potassium ion image sensor has been developed successfully. 32times32-pixels potassium ion image sensor was successfully fabricated by using CCD/CMOS image sensor technique and coating technology of organic responsive membranes. The sensor can take images of the concentration distribution of the potassium ion in the solution. Moreover, label free detection of potassium ion behavior related to living-cell activity is realized for the first time. The sensor could be an epoch-making device in the field of Bio-medical.
Keywords :
CCD image sensors; CMOS image sensors; biomedical imaging; biosensors; biotransport; cellular biophysics; potassium; 2D potassium ion image sensor; CCD image sensor; CMOS image sensor; K+; coating technology; label-free dynamic imaging; living cell activity; organic responsive membranes; Biomembranes; Biosensors; CMOS image sensors; CMOS technology; Charge coupled devices; Hydrogen; Image sensors; MOSFET circuits; Semiconductor films; Silicon; Image sensor; Responsive membrane; potassium ion;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International
Conference_Location :
Denver, CO
Print_ISBN :
978-1-4244-4190-7
Electronic_ISBN :
978-1-4244-4193-8
DOI :
10.1109/SENSOR.2009.5285937
