Title :
MEMS oxygen transporter to treat retinal ischemia
Author :
Dongyang Kang ; Murali, Karthik ; Scianmarello, Nicholas ; Jungwook Park ; Chang, Jay Han-Chieh ; Yang Liu ; Kai-Tang Chang ; Yu-chong Tai ; Humayun, Mark S.
Author_Institution :
California Inst. of Technol., Pasadena, CA, USA
Abstract :
For the first time, a paradigm shift in the treatment of retinal ischemia is proposed: providing localized supplemental oxygen to the ischemic tissue via an implanted MEMS device. A passive MEMS oxygen transporter is designed, built and tested in both artificial eye models and porcine cadaver eyes to confirm various hypotheses. The finite element modeling results predict that the proposed approach can treat complete retinal ischemia.
Keywords :
artificial organs; bioMEMS; biological tissues; biomedical equipment; eye; finite element analysis; patient treatment; artificial eye models; finite element modeling; implanted MEMS device; ischemic tissue; localized supplemental oxygen; paradigm shift; passive MEMS oxygen transporter; porcine cadaver eyes; retinal ischemia treatment; Cadaver; Mathematical model; Micromechanical devices; Permeability; Permeability measurement; Retina; Solid modeling;
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2015 28th IEEE International Conference on
Conference_Location :
Estoril
DOI :
10.1109/MEMSYS.2015.7050909
