A low-cost and label-free alpha-fetoprotein sensor based on self-assembled graphene on shrink polymer

Author

Sando, Shota ; Bo Zhang ; Tianhong Cui

Author_Institution

Univ. of Minnesota, Minneapolis, MN, USA

fYear

2015

fDate

18-22 Jan. 2015

Firstpage

324

Lastpage

327

Abstract

Self-assembled graphene by layer-by-layer (LbL) self-assembly on a shrink polymer substrate demonstrates nano wrinkles after heating. As a result, graphene with nano wrinkles shows different wettability and surface roughness, depending on shrink temperatures. The graphene on shrink polymer performs sensing applications for pH and alpha-fetoprotein (AFP) detection with advantages of low cost and label free, due to self-assembly technique, ease of modification, and antigen-antibody surface reaction.

Keywords

biochemistry; biomedical equipment; biosensors; electrochemical sensors; graphene; heat treatment; molecular biophysics; nanomedicine; nanosensors; pH; proteins; self-assembly; surface roughness; wetting; C; alpha-fetoprotein detection; antigen-antibody surface reaction; heating; label-free alpha-fetoprotein sensor; layer-by-layer self-assembly; nanowrinkles; pH; self-assembled graphene; shrink polymer substrate; shrink temperatures; surface roughness; wettability; Graphene; Heating; Immune system; Rough surfaces; Substrates; Surface roughness; Temperature measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro Electro Mechanical Systems (MEMS), 2015 28th IEEE International Conference on

Conference_Location

Estoril

Type

conf

DOI

10.1109/MEMSYS.2015.7050954

Filename

7050954