Title :
Detection of disease using lanthanide chelates as exogenous contrast enhancement markers and quantitative fluorescence endoscopy
Author :
Bornhop, D.J. ; Griffen, J. ; Stewart, Monique ; Sattu, P. ; Morgan, D.
Author_Institution :
Texas Tech. Univ., Lubbock, TX, USA
Abstract :
Summary form only given, as follows. Site-directed exogenous chemical markers used with fluorescence endoscopy have the potential for improving the detection and diagnosis of disease. We illustrate how minimally invasive imaging, using lanthanide chelates, can provide 80% sensitivity and 95% specificity for detection of cancerous lesions in the colon.
Keywords :
biomedical imaging; biomedical measurement; cancer; fluorescence; lanthanum compounds; laser applications in medicine; sensitivity; cancer detection; cancerous lesions; colon; disease detection; disease diagnosis; exogenous contrast enhancement markers; fluorescence endoscopy; lanthanide chelates; minimally invasive imaging; quantitative fluorescence endoscopy; sensitivity; site-directed exogenous chemical markers; specificity; Atom lasers; Cancer detection; Copper; Diseases; Gas lasers; Kinetic theory; Laser theory; Optical pulses; Power generation; Power lasers;
Conference_Titel :
Lasers and Electro-Optics, 1999. CLEO '99. Summaries of Papers Presented at the Conference on
Conference_Location :
Baltimore, MD, USA
Print_ISBN :
1-55752-595-1
DOI :
10.1109/CLEO.1999.834359