Title :
High Resolution and S/N Ratio Nano Probing System
Author :
Shuzo, M. ; Okada, K. ; Arai, H. ; Kanzaki, R. ; Shimoyama, I.
Author_Institution :
School of Information Science and Technology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan
Abstract :
Recently, not only recording the neural activity, but also simultaneous measurement of ion concentration from a single cell is necessary for biological function analysis. We presented a nanoprobe with calcium ion measurement in a cell using fluorescence. We´ve improved the performance of the nanoprobe by coating the aluminum on the pipette. Our glass micropipette coated with aluminum can measure fluorescence from a smaller area. Using this nanoprobing system, the fluorescence response from a tissue was measured every 10 µ m in depth.
Keywords :
Aluminum; Area measurement; Calcium; Cells (biology); Coatings; Fluorescence; Glass; Nanobioscience; Optical fibers; Optical imaging;
Conference_Titel :
Micro Electro Mechanical Systems, 2006. MEMS 2006 Istanbul. 19th IEEE International Conference on
Conference_Location :
Istanbul, Turkey
Print_ISBN :
0-7803-9475-5
DOI :
10.1109/MEMSYS.2006.1627858
