Title :
Analysis and prospective design for the treatment of cancer and AIDS by numerical simulation and supercomputer
Author :
Hausheer, Frederick H.
Author_Institution :
Dept. of Med./Med. Oncology, Texas Univ Health Sci. Center, San Antonio, TX, USA
Abstract :
Rational drug design by numerical simulation is considered. The application of a tightly coupled experimental and theoretical effort in drug development, which enables a greatly enhanced drug discovery effort in oncology and AIDS drug development, is urged. A specific example of this approach is presented. It deals with the formation of a stable DNA triple-helix complex targeted to cancer and AIDS therapy
Keywords :
medical computing; numerical analysis; patient treatment; AIDS treatment; cancer treatment; numerical simulation; rational drug design; stable DNA triple-helix complex; Acquired immune deficiency syndrome; Cancer; DNA; Diseases; Drugs; Human immunodeficiency virus; Medical treatment; Numerical simulation; Proteins; Supercomputers;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96509
