Title :
Compact voltage and current stimulation buffer for high-density microelectrode arrays
Author :
Livi, Paolo ; Heer, Flavio ; Frey, Urs ; Bakkum, Douglas J. ; Hierlemann, Andreas
Author_Institution :
ETH Zurich, Zurich, Switzerland
Abstract :
This paper presents the design and test of a reconfigurable buffer for voltage and current stimulation of electrogenic cells cultured on a CMOS microelectrode array. In voltage mode, the circuit is a high-current class-AB voltage follower, based on a local common-mode feedback. In current mode, the circuit is a current conveyor of type II, using the same amplifier with increased gain.
Keywords :
CMOS integrated circuits; bioMEMS; bioelectric phenomena; biomedical electrodes; buffer circuits; cellular biophysics; current conveyors; microelectrodes; neurophysiology; operational amplifiers; CMOS microelectrode array; amplifier; compact current stimulation buffer; compact voltage stimulation buffer; cultured electrogenic cells; high current class AB voltage follower; high density microelectrode arrays; local common mode feedback; reconfigurable buffer; type II current conveyor; Circuits; Electrical resistance measurement; Electrodes; Immune system; Microelectrodes; Neurons; Operational amplifiers; Resistors; Switches; Voltage;
Conference_Titel :
Solid-State Circuits Conference Digest of Technical Papers (ISSCC), 2010 IEEE International
Conference_Location :
San Francisco, CA
Print_ISBN :
978-1-4244-6033-5
DOI :
10.1109/ISSCC.2010.5433935
