Sensory-evoked potential using a non-invasive flexible multi-channel dry EEG electrode with vibration motor stimulation

Electroencephalography (EEG) of the mouse brain allows monitoring neural activity of brain in disease model. In response to demand for safer and efficient animal experimental methods, we demonstrate functional brain activity in mice using a novel non-invasive flexible multi-channel dry EEG electrode with high temporal resolution. The plunger-barrel-spring assembly structure of electrode pins containing inner spring enables each pin to fit tightly onto curved scalp surface. Also, longitudinal observation is possible in multiple mice with reusability and non-invasiveness resulted from structural characteristics. In our experimental set-up, we recorded sensory-evoked potential for 6 male C57BL/6 mice under vibrational mechanical stimulation of the hindlimb and analyzed the signal using topoplot.