DocumentCode
189678
Title
Robustness analysis of biomolecular networks
Author
Waldherr, Steffen
Author_Institution
Inst. for Autom. Eng., Otto-von-Guericke-Univ., Magdeburg, Germany
fYear
2014
fDate
24-27 June 2014
Firstpage
1176
Lastpage
1181
Abstract
Robustness is a widely studied property of biomolecular networks, and control engineers are in a good position to make significant contributions here. This tutorial defines common robustness analysis problems for biomolecular networks, presents computational methods to perform the analysis, and shows by means of examples what can be learned about a network from the analysis results. The focus is on deterministic methods applied to ordinary differential equation models of biomolecular networks.
Keywords
biology; deterministic algorithms; differential equations; molecular biophysics; biomolecular networks; computational methods; deterministic methods; ordinary differential equation models; robustness analysis problems; Bifurcation; Biological system modeling; Jacobian matrices; Mathematical model; Robustness; Steady-state;
fLanguage
English
Publisher
ieee
Conference_Titel
Control Conference (ECC), 2014 European
Conference_Location
Strasbourg
Print_ISBN
978-3-9524269-1-3
Type
conf
DOI
10.1109/ECC.2014.6862637
Filename
6862637
Link To Document