Title :
Real-time gene newtorks control in microfluidics
Author :
Menolascina, Filippo
Author_Institution :
Dept. of Civil & Environ. Eng., Massachusetts Inst. of Technol., Cambridge, MA, USA
Abstract :
This tutorial paper presents two examples of invivo real-time control of gene regulatory networks in the eukaryote S. cerevisiae (baker´s yeast). I discuss the theoretical and experimental challenges this problem poses and describe a microfluidics-based platform to address them. The results obtained using this setup demonstrate the proposed approach is both feasible and capable of achieving superior performances.
Keywords :
biocontrol; microfluidics; networked control systems; real-time systems; baker yeast; eukaryote S. cerevisiae; gene regulatory networks; microfluidics; microfluidics-based platform; real-time gene network control; Biological system modeling; Control systems; Integrated circuit modeling; Mathematical model; Proteins; Real-time systems; Sugar;
Conference_Titel :
Control Conference (ECC), 2014 European
Conference_Location :
Strasbourg
Print_ISBN :
978-3-9524269-1-3
DOI :
10.1109/ECC.2014.6862646
