Low-cost and high-performance micro-channel integrated biosensor systems

Author

Peng Li ; Gaoshan Jing ; Tianhong Cui ; Bo Zhang

Author_Institution

Dept. of Precision Instrum., Tsinghua Univ., Beijing, China

fYear

2014

fDate

2-5 Nov. 2014

Firstpage

1002

Lastpage

1005

Abstract

We presented a low-cost and high performance layer-by-layer (LBL) self-assembled carbon nanotube (CNT) biosensor with TiO₂ nanoparticles coated micro-channel integrated. The microfluidic channel surface is super hydrophilic after TiO₂ nanoparticle deposition and is capable of automating liquid sampling. It is able to give stable and precise results by consuming only 10 μl reagent, approximately, which facilitates portable application of such devices. The detection limit of lung cancer biomarker ENO1 could be achieved as low as 0.01 fg/ml, superior to most of the existing detection studies reported.

Keywords

bioMEMS; biomedical equipment; biosensors; cancer; carbon nanotubes; hydrophilicity; lung; microfluidics; microsensors; nanomedicine; nanoparticles; nanosensors; nanotube devices; self-assembly; titanium compounds; C-TiO₂; automating liquid sampling; hydrophilic; layer-by-layer self-assembled carbon nanotube biosensor; lung cancer biomarker ENO1 detection limit; microchannel integrated biosensor systems; microfluidic channel surface; nanoparticle deposition; Biosensors; Cancer; Lungs; Microfluidics; Nanoparticles; Sensor phenomena and characterization; TiO2; biosensor; carbon nanotube; micro-channel;

fLanguage

English

Publisher

ieee

Conference_Titel

SENSORS, 2014 IEEE

Conference_Location

Valencia

Type

conf

DOI

10.1109/ICSENS.2014.6985172

Filename

6985172