Title :
Integrated circuits for the biology-to-silicon interface [biotechnology]
Author :
Thewes, Roland ; Paulus, Christian ; Schienle, Meinrad ; Hofmann, Franz ; Frey, Alexander ; Brederlow, Ralf ; Schindler-Bauer, Petra ; Augustyniak, Marcin ; Atzesberger, Melanie ; Holzapfl, Birgit ; Jenkner, Martin ; Eversmann, Bjom ; Beer, Gottfried ; Fr
Author_Institution :
Corporate Res., Infineon Technol. AG, Munich, Germany
Abstract :
An overview is given of CMOS-based sensor- and actuator chips for in-vitro applications in the biotechnology area. We address the challenges and the potential of the combination of solid-state circuits with the wet world of bio molecules and living cells. Basic biological operating principles, market considerations, extended CMOS processing issues and concrete circuit examples are discussed.
Keywords :
CMOS integrated circuits; DNA; biomolecular electronics; biosensors; biotechnology; electrochemical analysis; microactuators; CMOS processing; CMOS-based actuators; CMOS-based sensors; DNA microarray chips; biology-to-silicon interface IC; biomolecules; biotechnology in-vitro equipment; cell handling; electrochemical sensors; living cells; Assembly; Biotechnology; CMOS process; CMOS technology; DNA; Drugs; Integrated circuit technology; Probes; Sequences; Testing;
Conference_Titel :
Solid-State Circuits Conference, 2004. ESSCIRC 2004. Proceeding of the 30th European
Print_ISBN :
0-7803-8480-6
DOI :
10.1109/ESSCIR.2004.1356607