Mechanisms of Anti-Inflammatory Effects of Low-Intensity Extremely High-Frequency Electromagnetic Radiation

Author

Gapeyev, A.B. ; Mikhailik, E.N. ; Chemeris, N.K.

Author_Institution

Inst. of Cell Biophys. of Russian Acad. Sci. Pushchino, Moscow

fYear

2007

fDate

10-14 Sept. 2007

Firstpage

30

Lastpage

32

Abstract

Using a model of acute zymosan-induced inflammation in NMRI mice, the dependence of anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation (EHF EMR) on frequency and intensity was found. The maximum decrease in footpad edema and hyperthermia by 20% was revealed at frequencies of 42.2, 51.8 and 65 GHz, intensity of 0.1 mW/cm² and exposure duration of 20 min. The pharmacological analysis has shown that arachidonic acid metabolites and histamine are involved in realization of anti-inflammatory effects of low-intensity EHF EMR.

Keywords

biological NMR; biological effects of microwaves; anti-inflammatory effects; arachidonic acid metabolites; extremely high-frequency electromagnetic radiation; footpad edema; frequency 42.2 GHz to 65 GHz; hyperthermia; time 20 min; zymosan-induced inflammation; Electromagnetic radiation; Frequency; In vitro; In vivo;

fLanguage

English

Publisher

ieee

Conference_Titel

Microwave & Telecommunication Technology, 2007. CriMiCo 2007. 17th International Crimean Conference

Conference_Location

Crimea

Print_ISBN

978-966-335-012-7

Type

conf

DOI

10.1109/CRMICO.2007.4368614

Filename

4368614