Optical Active Molecules used as Molecular Contrast Agents for Enhanced Imaging

Author

Giakos, G.C. ; Paturi, S. Atreya ; Valluru, K. ; Bathini, P. ; Ambadipudi, K. ; Adya, V. ; Sukumar, S. ; Sheffer, D.

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of Akron, Akron, OH

fYear

2008

fDate

12-15 May 2008

Firstpage

1809

Lastpage

1813

Abstract

A novel technique aimed at increasing the image contrast of a structure surrounded by a scattering medium, using optically active molecules as molecular contrast agents, is presented. Specifically, enhanced target detection was obtained by doping the surrounding medium with molecular contrast agents, consisting of aqueous glucose molecules, in conjunction to advanced polarimetric imaging techniques. The outcome of this study opens new horizons in the areas of molecular imaging, early disease detection and cancer identification.

Keywords

image enhancement; medical image processing; advanced polarimetric imaging techniques; aqueous glucose molecules; cancer identification; disease detection; enhanced imaging; enhanced target detection; image contrast; molecular contrast agents; molecular imaging; optical active molecules; optically active molecules; scattering medium; Biomedical optical imaging; Doping; Optical imaging; Optical polarization; Optical receivers; Optical retarders; Optical scattering; Optical sensors; Phase detection; Stokes parameters; Optical activity; Stokes parameters imaging; enhanced target detection techniques; metabolic imaging; molecular contrast agents and biomarkers;

fLanguage

English

Publisher

ieee

Conference_Titel

Instrumentation and Measurement Technology Conference Proceedings, 2008. IMTC 2008. IEEE

Conference_Location

Victoria, BC

ISSN

1091-5281

Print_ISBN

978-1-4244-1540-3

Electronic_ISBN

1091-5281

Type

conf

DOI

10.1109/IMTC.2008.4547338

Filename

4547338