Title :
A Real-time Instrumentation System for the Study of Regional Deposition of Airborne Particles and Drug Delivery in the Human Respiratory System
Author :
Gunarathne, G.P.P. ; Koujalagi, V. ; Semple, S. ; Ayres, J.G.
Author_Institution :
Sch. of Eng., Robert Gordon Univ., Aberdeen
Abstract :
This paper presents the work carried out in developing a precision, real-time bolus injection and breath-pattern analysis system to study the effect of regional deposition of fine particulate matter (PM) within the human respirator system. This new system computes parameters necessary and injects PM into breath cycles by a process of dynamic breadth pattern analysis and statistical data relating to PM stored under pressure taking into account such factors as agglomeration and aggregation of particles, to achieve a highly controlled delivery of bolus within specified exposure times and intervals.
Keywords :
drug delivery systems; respiratory protection; airborne particles; breath-pattern analysis system; drug delivery; human respirator system; human respiratory system; particle agglomeration; particle aggregation; particulate matter; real-time bolus injection; real-time instrumentation system; regional deposition; Air pollution; Control systems; Drug delivery; Humans; Instruments; Lungs; Nanoparticles; Pattern analysis; Real time systems; Respiratory system; Agglomeration; Air pollution; Bolus injection; Nanoparticles; Respiratory disorders;
Conference_Titel :
Instrumentation and Measurement Technology Conference Proceedings, 2008. IMTC 2008. IEEE
Conference_Location :
Victoria, BC
Print_ISBN :
978-1-4244-1540-3
Electronic_ISBN :
1091-5281
DOI :
10.1109/IMTC.2008.4547379
