An Ultra-Fast Computing Pipeline for Metagenome Analysis with Next-Generation DNA Sequencers

Metagenome analysis is useful for not only understanding symbiotic systems but also watching environment pollutions. However, metagenome analysis requires sensitive sequence homology searches which require large computation time and it is thus a bottleneck in current metagenome analysis based on the data from the latest DNA sequencers generally called a next-generation sequencer. To solve the problem, we developed a large-scale computing pipeline for metagenome analysis on TSUBAME2.