Title :
Probabilistic neural networks for multi-class tissue discrimination with gene expression data
Author :
Xu, Rui ; Wunsch, Donald C., II
Author_Institution :
Dept. of Electr. & Comput. Eng., Missouri Univ., Rolla, MO, USA
Abstract :
With the emergence and rapid advancement of DNA microarray technologies, construction of gene expression profiles for different cancer types has already become a promising means for cancer diagnosis and treatment. Most previous research has focused on binary classification. Here, we use a probabilistic neural network (PNN) for multi-classification of cancer data. The experimental results demonstrate the effectiveness of the PNN in addressing gene expression data.
Keywords :
DNA; cancer; medical computing; neural nets; pattern classification; probability; DNA microarray technologies; binary classification; cancer data; cancer diagnosis; cancer treatment; deoxyribonucleic acid; gene expression data; gene expression profiles; multiclass tissue discrimination; probabilistic neural networks; Cancer; Computational intelligence; DNA; Fluorescence; Gene expression; Laboratories; Medical treatment; Neoplasms; Neural networks; Uncertainty;
Conference_Titel :
Neural Networks, 2003. Proceedings of the International Joint Conference on
Print_ISBN :
0-7803-7898-9
DOI :
10.1109/IJCNN.2003.1223662