On-line monitoring and PET imaging of proton radiotherapy beams

Author

Litzenberg, D.W. ; Bajema, J.F. ; Becchetti, F.D. ; Brown, J.A. ; Raymond, R.S. ; Roberts, D.A. ; Caraher, J. ; Hutchins, G. ; Ronningen, R. ; Smith, R. ; Abbott, M.

Author_Institution

Michigan Univ., Ann Arbor, MI, USA

fYear

1992

fDate

25-31 Oct 1992

Firstpage

954

Abstract

Preliminary experiments have been performed which indicate that online localization of proton radiotherapy beams in tissue is feasible. Using a two-dimensional array of online sodium iodide (NaI) detectors it is possible to perform real-time monitoring of the production of positron emitting isotopes (mainly ¹¹C, ¹³N, and ¹⁵O) as a function of depth with pulsed proton beams of sufficiently low current. A commercial PET (positron emission tomography) scanner was used off-line to verify range and activity measurements. Results of range measurements using the two techniques are in good agreement with the calculated range, to within their respective resolutions

Keywords

computerised tomography; radiation therapy; radioisotope scanning and imaging; 2D detector array; ¹¹C; ¹³N; ¹⁵O; NaI; PET imaging; nuclear medicine; online localization; online monitoring; positron emission tomography; positron emitting isotopes production; proton radiotherapy beams; pulsed proton beams; real-time monitoring; Cyclotrons; Detectors; In vivo; Molecular beams; Monitoring; Neoplasms; Particle beams; Physics; Positron emission tomography; Protons;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium and Medical Imaging Conference, 1992., Conference Record of the 1992 IEEE

Conference_Location

Orlando, FL

Print_ISBN

0-7803-0884-0

Type

conf

DOI

10.1109/NSSMIC.1992.301095

Filename

301095