New Distance Measure for Microarray Gene Expressions Using Linear Dynamic Range of Photo Multiplier Tube

This paper deals with a new distance measure for genes using their microarray expressions. The distance measure is called, "maxrange distance ", where an experiment specific normalization factor is incorporated in the computation of the distance. The normalization factor is dependent on the linear dynamic range of the photo multiplier tube (PMT) for scanning fluorescence intensities of the gene expression values. Superiority of this distance measure in the microarray gene ordering problem has been extensively established on widely studied microarray data sets by performing statistical tests