Imaging molecular organization of cell membranes and proteins assemblies using polarimetric fluorescence microscopy

Biomolecular orientational organization is an important parameter in biological processes where functions (such as cell motility, vesicular trafficking, signalling, protein interactions, etc.) are closely related to orientation and ordering. The investigation of structural behaviors is today a determining factor for a better understanding of fundamental mechanisms governing cell membranes and proteins assemblies, which is particularly relevant for instance in neuro-degenerative diseases related to proteins aggregates formation.