Title :
A Novel Analysis Model for DNA Sequences
Author :
Jiang, Xianyang ; Yau, Stephen S T
Author_Institution :
Inst. of Microelectron. & Inf. Technol., Wuhan Univ., Wuhan
Abstract :
A novel analysis model for DNA sequence based on Stephen S.-T. Yau´s method is presented. The model adopts a trigonometric function to represent the four nucleotides A, G, C, and T in a DNA sequence, and has some interesting characteristics. Basing on the characteristics, statistical experiments on human gene coding regions show high possibility of significant peak at the frequency k = N/3 in their spectrum with respect to our model. The experimental results demonstrate potential application of the model in coding region detection.
Keywords :
DNA; genetics; molecular biophysics; DNA sequence analysis; coding region detection; nucleotides; trigonometric function; Biological system modeling; Biology computing; Biomedical engineering; Biomedical informatics; DNA computing; Humans; Information analysis; Mathematical model; Microelectronics; Sequences; Analysis model; DNA sequence; Discrete Fourier Transform (DFT); coding region detection; representation method;
Conference_Titel :
BioMedical Engineering and Informatics, 2008. BMEI 2008. International Conference on
Conference_Location :
Sanya
Print_ISBN :
978-0-7695-3118-2
DOI :
10.1109/BMEI.2008.199
