A Novel Analysis Model for DNA Sequences

Author

Jiang, Xianyang ; Yau, Stephen S T

Author_Institution

Inst. of Microelectron. & Inf. Technol., Wuhan Univ., Wuhan

Volume

1

fYear

2008

fDate

27-30 May 2008

Firstpage

24

Lastpage

28

Abstract

A novel analysis model for DNA sequence based on Stephen S.-T. Yau´s method is presented. The model adopts a trigonometric function to represent the four nucleotides A, G, C, and T in a DNA sequence, and has some interesting characteristics. Basing on the characteristics, statistical experiments on human gene coding regions show high possibility of significant peak at the frequency k = N/3 in their spectrum with respect to our model. The experimental results demonstrate potential application of the model in coding region detection.

Keywords

DNA; genetics; molecular biophysics; DNA sequence analysis; coding region detection; nucleotides; trigonometric function; Biological system modeling; Biology computing; Biomedical engineering; Biomedical informatics; DNA computing; Humans; Information analysis; Mathematical model; Microelectronics; Sequences; Analysis model; DNA sequence; Discrete Fourier Transform (DFT); coding region detection; representation method;

fLanguage

English

Publisher

ieee

Conference_Titel

BioMedical Engineering and Informatics, 2008. BMEI 2008. International Conference on

Conference_Location

Sanya

Print_ISBN

978-0-7695-3118-2

Type

conf

DOI

10.1109/BMEI.2008.199

Filename

4548629