Title :
Logit-transformation Based Confidence Intervals for the Sensitivity of a Continuous-scale Diagnostic Test
Author :
Kim, Jihye ; Qin, Gengsheng
Author_Institution :
Georgia State Univ., Atlanta, GA
Abstract :
In the field of modern medicine, diagnostic tests play an important role in detecting diseased patients. The diagnostic accuracy of a test is measured by its sensitivity and specificity. In this paper, we focus on the interval estimation for the sensitivity of a continuous-scale diagnostic test at a fixed level of its specificity. We propose two logit-transformation based confidence intervals for the sensitivity of a test and compare them with two of the best existing intervals (BTI and BTII) proposed by Zhou and Qin. Our simulation studies show that the newly proposed logit- transformation based intervals (LTI and LTII) have shorter interval lengths than the existing BTI and BTII intervals. The applications of the new intervals are illustrated in two real examples.
Keywords :
medical computing; patient diagnosis; continuous-scale diagnostic test; diagnostic accuracy; logit-transformation based confidence intervals; sensitivity; specificity; Biomedical engineering; Biomedical informatics; Biomedical measurements; Diseases; Life estimation; Medical diagnostic imaging; Medical simulation; Medical tests; Sensitivity and specificity; Testing;
Conference_Titel :
BioMedical Engineering and Informatics, 2008. BMEI 2008. International Conference on
Conference_Location :
Sanya
Print_ISBN :
978-0-7695-3118-2
DOI :
10.1109/BMEI.2008.348