FMRI mapping of motor-serial digit learning task in frontal lobe: methodological developments

A serial digit learning test (SDLT) is traditionally related to mesial temporal lobes. As sequencing is closely related to the frontal lobes, SDLT is also thought to activate these areas. In this paper, methodology used in the functional magnetic resonance imaging (fMRI) of the hypothesised frontal activations is presented. By the use of a specially designed variant task we were able to detect such activations. The absence of such findings in the relevant literature may originate from the lack of proper techniques for these activations.