Title :
Measurement of microscale bio-thermal responses by means of a micro-thermocouple probe
Author :
Kakuta, N. ; Suzuki, T. ; Saito, T. ; Nishimura, H. ; Mabuchi, K.
Author_Institution :
Center for Collaborative Res., Univ. of Tokyo, Japan
Abstract :
We developed a micro-thermocouple probe in order to measure the thermal responses of a cell. A micropipette with a tip 1 μm diameter was used for the base of the probe. A Pt/Au junction was constructed on the tip. The average thermoelectric power of the probe was 2.1 μV/K. The temperature and time resolutions of the probe were investigated by using a laser beam to irradiate the tip.
Keywords :
biological techniques; biothermics; cellular biophysics; probes; thermocouples; Pt-Au; Pt/Au junction; average thermoelectric power; biophysical research technique; cell thermal responses measurement; laser beam tip irradiation; micropipette; microscale biothermal responses measurement; microthermocouple probe; temperature resolution; time resolution; Atomic force microscopy; Cells (biology); Coatings; Glass; Gold; Polyimides; Probes; Spatial resolution; Temperature sensors; Thermoelectricity;
Conference_Titel :
Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
Print_ISBN :
0-7803-7211-5
DOI :
10.1109/IEMBS.2001.1017461
