Title :
Electrical and mechanical characterizations of dual nanoprobe for potential application of single cells analysis
Author :
Sulaiman, Abdul Hafiz Mat ; Ahmad, Mohd Ridzuan
Author_Institution :
Dept. of Mechatron. & Robotic, Univ. Teknol. Malaysia, Skudai, Malaysia
Abstract :
Electrical properties of a single cell can be used to infer about its physiological condition, e.g. cell viability. Conventional methods for electrical property measurement at single cell level are inaccurate, and have a slow throughput rate. Due to that, a dual nanoprobe-microfluidic system for electrical property measurement of single cells has been proposed. This paper is concerned about the mechanical and electrical characterizations of the dual nanoprobe. Electrical and mechanical characterizations have been conducted to measure the resistance and the strength of dual nanoprobe for five different materials i.e. Aluminium, Copper, Silver, Tungsten, and Zinc using finite element approach. From the findings, Tungsten´s nanoprobe has the highest strength while the resistance values for the five materials are not significantly different. Therefore, Tungsten has been chosen as the material for the dual nanoprobe.
Keywords :
aluminium; bioMEMS; bioelectric phenomena; cellular biophysics; copper; finite element analysis; microfluidics; nanofluidics; nanomedicine; nanosensors; silver; tungsten; zinc; Ag; Al; Cu; W; Zn; cell viability; dual nanoprobe-microfluidic system; electrical property measurement; electrical resistance; finite element approach; mechanical properties; physiological condition; single cell analysis; single cell level; Single cell; dual nanoprobe; electrical property; finite element method;
Conference_Titel :
Biomedical Engineering and Sciences (IECBES), 2012 IEEE EMBS Conference on
Conference_Location :
Langkawi
Print_ISBN :
978-1-4673-1664-4
DOI :
10.1109/IECBES.2012.6498162