Title :
Analysis of electrophysiological data in surgical treatment for Parkinson´s disease
Author :
Hamilton, Jennifer L. ; Micheli-Tzanakou, Evangelia ; Lehman, Richard
Author_Institution :
Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA
Abstract :
Current pharmacological therapy for Parkinson´s disease loses its usefulness over time. Recently, pallidotomy, a surgical treatment for many of the symptoms of Parkinson´s, has been re-investigated. This procedure requires localization of a small region within the globus pallidus. In this paper, the authors present a simple mathematical analysis of spontaneous neural activity which has been used to refine targeting derived from magnetic resonance imaging (MRI)
Keywords :
bioelectric potentials; diseases; medical signal processing; neurophysiology; surgery; Parkinson´s disease; electrophysiological data analysis; globus pallidus region localization; magnetic resonance imaging; pallidotomy; pharmacological therapy; simple mathematical analysis; spontaneous neural activity; surgical treatment; targeting refinement; Biomedical engineering; Data analysis; Electrodes; Electrophysiology; Lesions; Magnetic resonance imaging; Medical treatment; Neurosurgery; Parkinson´s disease; Surgery;
Conference_Titel :
Bioengineering Conference, 1998. Proceedings of the IEEE 24th Annual Northeast
Conference_Location :
Hershey, PA
Print_ISBN :
0-7803-4544-4
DOI :
10.1109/NEBC.1998.664858
