Title :
A portable system for quantitative assessment of parkinsonian bradykinesia during deep-brain stimulation surgery
Author :
Dai, Houde ; D´Angelo, L.T.
Author_Institution :
Inst. of Micro Technol. & Med. Device Technol., Tech. Univ. Muenchen, Munich, Germany
Abstract :
Deep-brain stimulation is the most effective surgical treatment for severe Parkinson´s disease (PD). Bradykinesia is one of the primary symptoms of PD. 10 s hand grasping movement is used to assess bradykinesia severity in this study. An inertial measurement unit (IMU), which is attached to the middle finger, is used to measure the angular displacement of the middle finger movement during bradykinesia assessment task. The dominant grasping frequency, mean value and standard deviation (SD) of hand grasping ranges are used as the severity features of bradykinesia. Three healthy subjects and four PD patients were tested by the wearable system. The modified mean range correlated well with the 5-point clinical ratings. Further clinical experiments will be performed in the near future.
Keywords :
angular velocity measurement; biomechanics; brain; diseases; medical signal processing; patient diagnosis; patient treatment; portable instruments; surgery; wearable computers; IMU-measured angular displacement; angular displacement measurement; bradykinesia assessment task; bradykinesia severity assessment; bradykinesia severity features; deep-brain stimulation surgery; dominant grasping frequency; effective surgical treatment; hand grasping movement-assessed bradykinesia severity; hand grasping range SD; hand grasping range mean value; hand grasping range standard deviation; middle finger movement; middle finger-attached IMU; middle finger-attached inertial measurement unit; modified mean range clinical rating correlation; portable parkinsonian bradykinesia assessment system; primary PD symptom; primary Parkinson´s disease symptom; quantitative parkinsonian bradykinesia assessment; severe PD symptom; severe Parkinson´s disease symptom; time 10.00 s; wearable system-tested PD patient; wearable system-tested Parkinson´s disease patient; Accelerometers; Grasping; Gyroscopes; Parkinson´s disease; Satellite broadcasting; Thumb; MEMS inertial sensor; Parkinson´s disease; bradykinesia; deep brain stimulation; neuroprosthesis;
Conference_Titel :
Advances in Biomedical Engineering (ICABME), 2013 2nd International Conference on
Conference_Location :
Tripoli
Print_ISBN :
978-1-4799-0249-1
DOI :
10.1109/ICABME.2013.6648851
