Title :
Feature selection and classification by using grid computing based evolutionary approach for the microarray data
Author :
Chen, T.-C. ; Hsieh, Y.-C. ; You, P.-S. ; Lee, Y.-C.
Author_Institution :
Dept. of Inf. Manage., Nat. Formosa Univ., Huwei, Taiwan
Abstract :
The cancer classification through gene expression patterns becomes one of the most promising applications of the microarray technology. It is also a significant procedure in bioinformatics. In this study a grid computing based evolutionary mining approach is proposed as discriminant function for gene selection and tumor classification. The proposed approach is based on the grid computing infrastructure for establishing the best attributes set. The discriminant analysis based on vector distant of median method as the evaluation function of genetic algorithm which lays stress on find the key attributes set of the data set to establish the best attributes set for constructing a classification response model with highest accuracy. We show experimentally that the proposed approach for several benchmarking cancer microarray data sets can work effectively and efficiently, and the results of the proposed methods are superior to or as well as other existing methods in literatures.
Keywords :
cancer; data mining; evolutionary computation; genetic algorithms; grid computing; medical computing; tumours; bioinformatics; cancer classification; classification response model; discriminant function; evolutionary mining approach; feature selection; gene expression patterns; gene selection; genetic algorithm; grid computing; median method; microarray data; tumor classification; Accuracy; Benchmark testing; Servers; Training; genetic algorithm; grid computing; microarray; tumor classification;
Conference_Titel :
Computer Science and Information Technology (ICCSIT), 2010 3rd IEEE International Conference on
Conference_Location :
Chengdu
Print_ISBN :
978-1-4244-5537-9
DOI :
10.1109/ICCSIT.2010.5564986