Title :
Cell affinity of PHBV thin films evaluated by a parallel plate flow chamber
Author :
Yuping Zhang ; Wang, Yanyan ; Lanxin, L.V. ; Yan, Shancheng ; Haitao Wang ; Zhang, Yong ; Zhu, Dalong ; Ningping Huang ; Xiao, Zhongdang
Author_Institution :
State Key Lab. of Bioelectronics, Southeast Univ., Nanjing
Abstract :
The aim of the study is to evaluate the cell affinity of poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) (PHBV) thin films using a parallel plate flow chamber system. The PHBV thin films were modified by anhydrous ammonia gaseous plasma treatment. Mouse 3T3 fibroblast cells were seeded on bare and plasma modified PHBV thin films, respectively. A laminar flow enforces the cells on these films in a parallel plate flow chamber system. The percentage of initial cells remaining on the films after serials flows was used to evaluate the cell affinity of films. The results showed that, compared with control groups, ammonia plasma treatment could promote the cell affinity of PHBV films. It also indicated that the parallel plate flow chamber system can be used to evaluate the cell affinity of a material.
Keywords :
biomedical materials; cellular biophysics; laminar flow; plasma applications; polymer films; PHBV thin films; anhydrous ammonia gaseous plasma treatment; cell affinity; laminar flow; mouse 3T3 fibroblast cells; parallel plate flow chamber; poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid); Transistors; Poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) (PHBV); cell affinity; parallel plate flow chamber (PPFC); plasma treatment;
Conference_Titel :
Nano/Micro Engineered and Molecular Systems, 2009. NEMS 2009. 4th IEEE International Conference on
Conference_Location :
Shenzhen
Print_ISBN :
978-1-4244-4629-2
Electronic_ISBN :
978-1-4244-4630-8
DOI :
10.1109/NEMS.2009.5068665
