Design of a Holding System for Micro-coil based MRI

Author

Ekekwe, N. ; Armiger, B. ; Murray, K.

Author_Institution

Johns Hopkins Univ., Baltimore

fYear

2007

fDate

Aug. 12 2007-July 16 2007

Firstpage

73

Lastpage

74

Abstract

We report the design and fabrication of a holding cell system that enables concurrent image visualization of a single cell during planar micro-coil based magnetic resonance imaging (MRI) at cellular level. The present hardware design of many micro-coil based MRI systems prevents monitoring of cell interactions and compositions during MRI. The system, fabricated on a poly dimethyl siloxane (PDMS) structure using soft lithography on a glass substrate, is designed to solve this problem. To test it, a laser beam would be coupled into the chip to acquire images of a frog oocyte.

Keywords

biological techniques; cellular biophysics; sample holders; soft lithography; cell interactions; concurrent image visualization; frog oocyte; glass substrate; holding system design; laser beam coupling; magnetic resonance imaging; microcoil based MRI; poly dimethyl siloxane; single cell visualization; soft lithography; Fabrication; Glass; Hardware; Laser beams; Magnetic resonance imaging; Monitoring; Optical coupling; Soft lithography; Testing; Visualization; MRI; planar coil; soft lithography;

fLanguage

English

Publisher

ieee

Conference_Titel

Optical MEMS and Nanophotonics, 2007 IEEE/LEOS International Conference on

Conference_Location

Hualien

Print_ISBN

978-1-4244-0641-8

Type

conf

DOI

10.1109/OMEMS.2007.4373846

Filename

4373846