Mathematical model of venous occlusion plethysmography for diagnosing deep vein thrombosis

Although the results of venous occlusion plethysmography (VOP) can determine the existence of deep vein thrombosis (DVT), it is difficult to analyze quantitatively the effects of the degrees of thrombosis, blood pressure and cuff pressure on VOP. In this paper, by developing a combined model that is composed of a pulsatile cardiovascular model and a venous occlusion model, we showed the availability of a more realistic simulation. Using the proposed combined model for simulation of the effects of different head pressures and degrees of thrombosis on VOP, we can achieve a basic understanding of the relationship between the state of the patient and indirect measurements such as impedance plethysmography (IPG) and strain gauge plethysmography (SPG).