256-site active neural probe and 64-channel responsive cortical stimulator

Author

Shulyzki, R. ; Abdelhalim, K. ; Bagheri, A. ; Florez, C.M. ; Carlen, P.L. ; Genov, R.

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of Toronto, Toronto, ON, Canada

fYear

2011

fDate

19-21 Sept. 2011

Firstpage

1

Lastpage

4

Abstract

The 0.35μm CMOS active probe and stimulator enables responsive neural stimulation of the brain cortex. It monitors extracellular neural activity on 256 sites in the brain and generates 64 event-triggered current-mode neural stimuli. Each 0.035mm² fully differential neural recording channel includes a 8-bit single slope ADC. Each 0.02mm² neural stimulation channel reuses an OTA for both current sampling and current sourcing. The 13.5mW prototype is flip-chip bonded with a 64-shank Utah electrode array and validated in spatial recording of epileptic neural activity in the mouse hippocampus.

Keywords

CMOS integrated circuits; analogue-digital conversion; biomedical electrodes; brain; flip-chip devices; operational amplifiers; prosthetics; 64- shank Utah electrode array; 64-channel responsive cortical stimulator; CMOS active neural probe stimulator; OTA; brain cortex; current sampling; current sourcing; epileptic neural activity spatial recording; event-triggered current-mode neural stimuli; extracellular neural activity; flip-chip prototype; fully differential neural recording channel; implantable responsive neural stimulation system; mouse hippocampus; neural stimulation channel; power 13.5 mW; single slope ADC; size 0.35 mum; word length 8 bit; Arrays; CMOS integrated circuits; Electrodes; Noise; Noise measurement; Power dissipation; Prototypes;

fLanguage

English

Publisher

ieee

Conference_Titel

Custom Integrated Circuits Conference (CICC), 2011 IEEE

Conference_Location

San Jose, CA

ISSN

0886-5930

Print_ISBN

978-1-4577-0222-8

Type

conf

DOI

10.1109/CICC.2011.6055371

Filename

6055371