Title :
256-site active neural probe and 64-channel responsive cortical stimulator
Author :
Shulyzki, R. ; Abdelhalim, K. ; Bagheri, A. ; Florez, C.M. ; Carlen, P.L. ; Genov, R.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Toronto, Toronto, ON, Canada
Abstract :
The 0.35μm CMOS active probe and stimulator enables responsive neural stimulation of the brain cortex. It monitors extracellular neural activity on 256 sites in the brain and generates 64 event-triggered current-mode neural stimuli. Each 0.035mm2 fully differential neural recording channel includes a 8-bit single slope ADC. Each 0.02mm2 neural stimulation channel reuses an OTA for both current sampling and current sourcing. The 13.5mW prototype is flip-chip bonded with a 64-shank Utah electrode array and validated in spatial recording of epileptic neural activity in the mouse hippocampus.
Keywords :
CMOS integrated circuits; analogue-digital conversion; biomedical electrodes; brain; flip-chip devices; operational amplifiers; prosthetics; 64- shank Utah electrode array; 64-channel responsive cortical stimulator; CMOS active neural probe stimulator; OTA; brain cortex; current sampling; current sourcing; epileptic neural activity spatial recording; event-triggered current-mode neural stimuli; extracellular neural activity; flip-chip prototype; fully differential neural recording channel; implantable responsive neural stimulation system; mouse hippocampus; neural stimulation channel; power 13.5 mW; single slope ADC; size 0.35 mum; word length 8 bit; Arrays; CMOS integrated circuits; Electrodes; Noise; Noise measurement; Power dissipation; Prototypes;
Conference_Titel :
Custom Integrated Circuits Conference (CICC), 2011 IEEE
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-4577-0222-8
DOI :
10.1109/CICC.2011.6055371
