DocumentCode :
1967137
Title :
Channel capacity of calcium signalling based on inter-cellular calcium waves in astrocytes
Author :
Heren, Akif Cem ; Kuran, Mehmet Sukru ; Yilmaz, H. Birkan ; Tugcu, Tuna
Author_Institution :
Dept. of Comput. Eng., Bogazici Univ., Istanbul, Turkey
fYear :
2013
fDate :
9-13 June 2013
Firstpage :
792
Lastpage :
797
Abstract :
In this paper we investigate the channel capacity of the calcium signalling system based on an inter-cellular calcium wave model for astrocytes in the literature. Calcium signalling is a good candidate for molecular communication due to its long communication range, possible usage of existing cellular infrastructure, and its minimally invasive nature. Calcium waves are formed by the cytosolic oscillations of Ca2+ ion concentration, which propagates through neighbouring cells via secondary messenger molecules. Understanding the dynamics and physical properties of inter-cellular calcium waves is expected to produce an effective solution for the nano device communication problem. Thus, we extend the models developed in the literature to offer a calcium signalling scheme built on two cells and investigate the channel capacity depending on noise level and symbol duration. To the best of our knowledge, this is the first channel capacity analysis of calcium wave model that includes intercellular dynamics.
Keywords :
bioelectric phenomena; biomembrane transport; calcium; molecular biophysics; Ca; astrocytes; calcium signalling system; cellular infrastructure; channel capacity analysis; cytosolic oscillation; intercellular calcium wave model; ion concentration; molecular communication; nanodevice communication problem; secondary messenger molecule; Calcium; Channel capacity; Equations; Mathematical model; Noise; Noise level; Oscillators;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Communications Workshops (ICC), 2013 IEEE International Conference on
Conference_Location :
Budapest
Type :
conf
DOI :
10.1109/ICCW.2013.6649341
Filename :
6649341
Link To Document :
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