• DocumentCode
    1970526
  • Title

    Microfluidic chip coupled with optical molecular imaging for behavior analysis

  • Author

    Liu, Bi-Feng ; Wang, Jingjing ; Feng, Xiaojun ; Du, Wei

  • Author_Institution
    Dept. of Syst. Biol., Huazhong Univ. of Sci. & Technol., Wuhan, China
  • fYear
    2010
  • fDate
    8-12 Dec. 2010
  • Firstpage
    687
  • Lastpage
    688
  • Abstract
    We demonstrate a microfluidic system allowing stable immobilization of young adult C. elegans for neuronal and behavior analysis upon chemical stimulations. Chemical stimuli were delivered to the head of the animal by rapid interface shifting of laminar flows and neuronal activities could then be monitored by in vivo Ca2+ imaging.
  • Keywords
    bioMEMS; biochemistry; biomedical optical imaging; lab-on-a-chip; microfluidics; microorganisms; neurophysiology; behavior analysis; chemical stimuli; in vivo Ca2+ imaging; laminar flows; microfluidic chip; neuronal analysis; optical molecular imaging; rapid interface shifting; young adult C. elegans immobilization; Animals; Chemicals; Imaging; In vivo; Microfluidics; Neurons;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Communications and Photonics Conference and Exhibition (ACP), 2010 Asia
  • Conference_Location
    Shanghai
  • Print_ISBN
    978-1-4244-7111-9
  • Type

    conf

  • DOI
    10.1109/ACP.2010.5682690
  • Filename
    5682690
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1970526