• DocumentCode
    1973417
  • Title

    Clinical translation of UV autofluorescence microscopy towards endomicroscopy for early detection of cancer

  • Author

    Lin, Bevin ; Urayama, Shiro ; Saroufeem, Ramez M.G. ; Matthews, Dennis L. ; Demos, Stavros G.

  • Author_Institution
    NSF Center for Biophotonics Sci. & Technol., Univ. of California, Davis, Sacramento, CA, USA
  • fYear
    2010
  • fDate
    8-12 Dec. 2010
  • Firstpage
    44
  • Lastpage
    45
  • Abstract
    The non-invasiveness of autofluorescence technology may reduce sampling error and time delay for histopathology diagnosis. We establish biophotonic methods and guidelines to visualize and interpret early epithelial tissue changes that signify disease. Flexible and rigid fiber endomicroscopy instrumentation design parameters feasible for translation towards clinical use are in development.
  • Keywords
    bio-optics; biomedical optical imaging; cancer; endoscopes; fluorescence; optical microscopy; patient diagnosis; UV autofluorescence microscopy; biophotonic methods; cancer detection; epithelial tissue changes; flexible fiber endomicroscopy; histopathology diagnosis; rigid fiber endomicroscopy; sampling error; time delay; Endoscopes; Gold; In vivo; Microscopy; Prototypes; Real time systems;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Communications and Photonics Conference and Exhibition (ACP), 2010 Asia
  • Conference_Location
    Shanghai
  • Print_ISBN
    978-1-4244-7111-9
  • Type

    conf

  • DOI
    10.1109/ACP.2010.5682843
  • Filename
    5682843