Title :
Raman spectroscopy of serum for cancer detection
Author :
Li, Xiaozhou ; Jin, Huiqiang
Author_Institution :
Biol. Dept., Liaoning Univ., Shenyang, China
Abstract :
Laser induced auto-fluorescence and Raman spectra of serum from cancerous and normal people are measured and analyzed. Three Raman peaks were consistently observed from normal blood serum emission using 488.0 nm and 514.5 nm excitation of an Ar-ion laser, whereas no peak or only slight Raman peaks were detected from the tumorous cases. The content of -carotene in the normal serum is higher than that from the cancerous serum. This result agrees with other reports.
Keywords :
Raman spectroscopy; biochemistry; blood; cancer; fluorescence spectroscopy; laser applications in medicine; patient diagnosis; spectrochemical analysis; 488.0 nm; 514.5 nm; Ar; Ar-ion laser; cancerous people; cancerous serum; carcinoma; carotene; chromophores; flavins; molecular structure; normal blood serum emission; normal people; optical tools; porphyrins; protein; riboflavin; slight Raman peaks; well-defined visible fluorescence spectroscopy; Absorption; Blood; Cancer detection; Fluorescence; Laser excitation; Laser theory; Laser transitions; Raman scattering; Spectroscopy; Wavelength measurement;
Conference_Titel :
Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
Print_ISBN :
0-7803-7211-5
DOI :
10.1109/IEMBS.2001.1019508
