• DocumentCode
    1982273
  • Title

    Investigation of collagen changes in sclerodermatous skin using second harmonic generation microscopy

  • Author

    Lu, Kecheng ; Chen, Jianxin ; Zhuo, Shuangmu ; Zheng, Liqin ; Jiang, Xingshan ; Zhu, Xiaoqin ; Zhao, Jingjun

  • Author_Institution
    Fujian Provincial Key Lab. for Photonics Technol., Fujian Normal Univ., Fuzhou, China
  • fYear
    2009
  • fDate
    30-3 Aug. 2009
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    The changes of collagen in sclerodermatous skin were investigated qualitatively and quantitatively using second harmonic generation (SHG) microscopy. The technique has great potential to be used to diagnose scleroderma and monitor the therapy response.
  • Keywords
    optical harmonic generation; optical microscopy; proteins; skin; collagen changes; sclerodermatous skin; second harmonic generation microscopy; Biomedical imaging; Dermis; Educational technology; Epidermis; Fast Fourier transforms; Frequency conversion; Laboratories; Laser excitation; Microscopy; Skin; collagen; localized scleroderma; second harmonic generation;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers & Electro Optics & The Pacific Rim Conference on Lasers and Electro-Optics, 2009. CLEO/PACIFIC RIM '09. Conference on
  • Conference_Location
    Shanghai
  • Print_ISBN
    978-1-4244-3829-7
  • Electronic_ISBN
    978-1-4244-3830-3
  • Type

    conf

  • DOI
    10.1109/CLEOPR.2009.5292663
  • Filename
    5292663