• DocumentCode
    1988524
  • Title

    A new method for predicting RNA secondary structure

  • Author

    Taira, Hirotoshi ; Izumitani, Tomonori ; Maeda, Eisaku ; Suzuki, Takeshi

  • Author_Institution
    NTT Commun. Sci. Labs., Kyoto, Japan
  • fYear
    2003
  • fDate
    11-14 Aug. 2003
  • Firstpage
    521
  • Lastpage
    522
  • Abstract
    It has become clear recently that there are many RNAs that are not translated into proteins, instead they work as functional molecules. These RNAs are called "noncoding RNAs." Predicting the secondary structure of these RNAs is important for understanding their functions. We focus on Nussinov\´s algorithm and the SCFG version of Nussinov\´s algorithm as useful techniques for predicting RNA secondary structures. We introduce a new scoring table and loop length restriction to improve these algorithms, and the improved algorithms provided better levels of performance than the originals.
  • Keywords
    biological techniques; dynamic programming; genetic algorithms; macromolecules; molecular biophysics; organic compounds; Nussinov algorithm; RNA secondary structure; SCFG version; noncoding RNA; Accuracy; Dynamic programming; Heuristic algorithms; Hydrogen; Laboratories; Niobium; Prediction algorithms; Proteins; RNA; Shape;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics Conference, 2003. CSB 2003. Proceedings of the 2003 IEEE
  • Print_ISBN
    0-7695-2000-6
  • Type

    conf

  • DOI
    10.1109/CSB.2003.1227395
  • Filename
    1227395