DocumentCode :
1988524
Title :
A new method for predicting RNA secondary structure
Author :
Taira, Hirotoshi ; Izumitani, Tomonori ; Maeda, Eisaku ; Suzuki, Takeshi
Author_Institution :
NTT Commun. Sci. Labs., Kyoto, Japan
fYear :
2003
fDate :
11-14 Aug. 2003
Firstpage :
521
Lastpage :
522
Abstract :
It has become clear recently that there are many RNAs that are not translated into proteins, instead they work as functional molecules. These RNAs are called "noncoding RNAs." Predicting the secondary structure of these RNAs is important for understanding their functions. We focus on Nussinov\´s algorithm and the SCFG version of Nussinov\´s algorithm as useful techniques for predicting RNA secondary structures. We introduce a new scoring table and loop length restriction to improve these algorithms, and the improved algorithms provided better levels of performance than the originals.
Keywords :
biological techniques; dynamic programming; genetic algorithms; macromolecules; molecular biophysics; organic compounds; Nussinov algorithm; RNA secondary structure; SCFG version; noncoding RNA; Accuracy; Dynamic programming; Heuristic algorithms; Hydrogen; Laboratories; Niobium; Prediction algorithms; Proteins; RNA; Shape;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics Conference, 2003. CSB 2003. Proceedings of the 2003 IEEE
Print_ISBN :
0-7695-2000-6
Type :
conf
DOI :
10.1109/CSB.2003.1227395
Filename :
1227395
Link To Document :
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