A Compartmentalized Approach to the Assembly of Physical Maps

Author

Bozdag, Serdar ; Close, Timothy J. ; Lonardi, Stefano

Author_Institution

Univ. of California, Riverside

fYear

2007

fDate

14-17 Oct. 2007

Firstpage

218

Lastpage

225

Abstract

We propose a novel compartmentalized method for the assembly of physical maps from fingerprinted clones. Our assembler exploits the presence of genetic markers at the global level to improve the accuracy of the assembly. Experimental results on the genome of rice and barley demonstrate that the compartmentalized assembler produces significantly more accurate maps, and that it can detect and isolate clones that induce chimeric contigs.

Keywords

biology computing; cellular biophysics; genetics; barley; chimeric contigs; chromosome; compartmentalized approach; fingerprinted clones; genetic markers; genome; physical maps; rice; Assembly; Biochemistry; Bioinformatics; Cloning; Electrokinetics; Fingerprint recognition; Flexible printed circuits; Genetics; Genomics; Probes;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on

Conference_Location

Boston, MA

Print_ISBN

978-1-4244-1509-0

Type

conf

DOI

10.1109/BIBE.2007.4375568

Filename

4375568

Link To Document

https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1989073