Title :
A Compartmentalized Approach to the Assembly of Physical Maps
Author :
Bozdag, Serdar ; Close, Timothy J. ; Lonardi, Stefano
Author_Institution :
Univ. of California, Riverside
Abstract :
We propose a novel compartmentalized method for the assembly of physical maps from fingerprinted clones. Our assembler exploits the presence of genetic markers at the global level to improve the accuracy of the assembly. Experimental results on the genome of rice and barley demonstrate that the compartmentalized assembler produces significantly more accurate maps, and that it can detect and isolate clones that induce chimeric contigs.
Keywords :
biology computing; cellular biophysics; genetics; barley; chimeric contigs; chromosome; compartmentalized approach; fingerprinted clones; genetic markers; genome; physical maps; rice; Assembly; Biochemistry; Bioinformatics; Cloning; Electrokinetics; Fingerprint recognition; Flexible printed circuits; Genetics; Genomics; Probes;
Conference_Titel :
Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-1509-0
DOI :
10.1109/BIBE.2007.4375568
